Interferon Lambda Alleles Predict Innate Antiviral Immune Responses and Hepatitis C Virus Permissiveness
نویسندگان
چکیده
منابع مشابه
Interferon lambda alleles predict innate antiviral immune responses and hepatitis C virus permissiveness.
Hepatitis C virus (HCV) infection can result in viral chronicity or clearance. Although host genetics and particularly genetic variation in the interferon lambda (IFNL) locus are associated with spontaneous HCV clearance and treatment success, the mechanisms guiding these clinical outcomes remain unknown. Using a laser capture microdissection-driven unbiased systems virology approach, we isolat...
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ژورنال
عنوان ژورنال: Cell Host & Microbe
سال: 2014
ISSN: 1931-3128
DOI: 10.1016/j.chom.2014.01.007